Next-Generation Diagnostics
The first new approach to rapid diagnostics since the home pregnancy test appeared in drugstores almost 50 years ago
No Blood Needed
Bloodless Dx transforms the body's own biology into a real-time diagnostic system.
Why it is Different
Bloodless Dx Technology
Bloodless Dx transforms the body's own biology into a real-time diagnostic system. The test acts as a tiny analyzer with continuous access to a replenishing biological sample.
Instead of bringing the sample to the test, Bloodless Dx brings the test to the sample.
Traditional diagnostics collect a small volume of blood or other bodily fluid and bring that sample to a test.
Bloodless Dx takes a fundamentally different approach.
The test is placed in the skin, where it can continuously encounter target molecules moving through the body's interstitial fluid.
That eliminates specimen collection while providing access to sample.
Why Bloodless?
A diagnostic test that works with the body—not outside it
No Specimen Collection
No blood draw, urine collection, or sample processing.
One-Step Application
The test is applied directly to the skin using a simple applicator.
Direct Visual Readout
Target detection generates a localized, visible biological response.
Continuous Access to the Sample
Rather than analyzing a single collected specimen, the test remains positioned within the body's continuously replenished interstitial fluid.
A Fundamentally Different Approach
See how Bloodless Dx compares with a conventional rapid diagnostic test
A New Diagnostic Capability
A diagnostic test designed not only to detect—but to monitor.
Bloodless Dx tests are applied to the dermal layer of the skin, where they can detect target analytes moving through the interstitial fluid. If the target is detected, a localized visible response is generated. If the target is not initially present, the test has the potential to remain active and monitor for subsequent exposure until activated—operating as a biological sentinel.
Diagnostic + Sentinel
Detect now—or monitor for what comes next
Is the target present now?
Apply the test and observe the site for a localized response indicating detection of the target analyte.
Does the target appear later?
A Bloodless Dx test can remain active after application until activated, creating the potential to monitor for subsequent exposure.
A diagnostic test becomes a biological sentinel.
Applications
From Detection to Action
Bloodless Dx isn't just a new way to run a diagnostic test. The platform could change when, where and how disease is detected.
Reduce Transmission
Monitor exposed individuals and detect infection early enough to support timely treatment and reduce onward transmission.
Monitor After Exposure
Provide a potential Sentinel for individuals following a known or suspected exposure, enabling earlier detection during outbreaks such as Ebola.
Detect Disease Earlier
Detect rapidly changing biomarkers in time-critical conditions such as neonatal sepsis, potentially enabling earlier clinical intervention.
Decentralize Testing
Bring sophisticated biological detection closer to the patient without conventional specimen collection or laboratory infrastructure.
Potential Disease Targets
Malaria | Tuberculosis | Ebola | Influenza | Sepsis Biomarkers | Emerging Infectious Diseases
The Bigger Vision
What if a diagnostic test didn't require a sample at all?
Bloodless Dx is developing a new class of diagnostics that uses the body itself as part of the detection system. By combining engineered affinity reagents with the body's natural immune signaling mechanisms, we envision diagnostics that are simpler, faster, more accessible—and capable of monitoring as well as testing.
No laboratory. No instrument. No specimen collection.
Just the patient and the test.
Get In Touch
Contact
Interested in Bloodless Dx technology, research collaborations, or potential applications? We would be pleased to hear from you.
The Sentinel approach could enable monitoring of healthcare workers and others at risk of exposure to infectious disease.